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Raj Mutharasan

Frank A. Fletcher Professor

Office CAT 281
Phone 215-895-2236
Fax 215-895-5837
Email mutharasan@drexel.edu
Website Mutharasan Lab Website
Curriculum Vitae Mutharasan CV
Google Scholar Citations http://scholar.google.com/citations?hl=en&user=QlcfDqwAAAAJ&view_op =list_works&pagesize=100


PhD, Chemical Engineering, Drexel University, 1973
MS, Chemical Engineering, Drexel University, 1971
BS, Chemical Engineering, IIT (Madras, India), 1969

Research Interests

  • Biosensor based on optical, electromechanical (cantilevers, shear wave), and magnetoelastic phenomena. Applications include food, environment, biowarfare, and medical.
  • Detection of cancer signatures, DNA hybridization, self assembled monolayer characterization
  • Behavior of protein interfaces; antigen-antibody reaction in non-aqueous environment
  • Mathematical modeling of biological phenomena

Recent Publications

Johnson, B.; Mutharasan, R. Biosensor-based MicroRNA Detection: Techniques, Design, Performance, and Challenges. Analyst 2014, 139 (7), 1576 - 1588.

Johnson, B.; Mutharasan, R. Reduction of nonspecific protein adsorption on cantilever biosensors caused by transverse resonant mode vibration. Analyst 2014, 139 (5), 1112 - 1120.

Rosario, R.; Mutharasan, R. Piezoelectric excited millimeter sized cantilever sensors for measuring gas density changes. Sens. Actuators, B 2014, 192, 99-104.

Johnson, B.; Mutharasan, R. A cantilever biosensor-based assay for toxin-producing cyanobacteria Microcystis aeruginosa using 16S rRNA. Envir Sci Tech 2013, in press.

Johnson, B. N.; Mutharasan, R. Electrochemical piezoelectric-excited millimeter-sized cantilever (ePEMC) for simultaneous dual transduction biosensing. Analyst 2013, 138 (21), 6365 - 6371.

Johnson, B. N.; Mutharasan, R. Regeneration of Gold Surfaces Covered by Adsorbed Thiols and Proteins Using Liquid-Phase Hydrogen Peroxide-Mediated UV-Photooxidation. J. Phys. Chem. 2013, 117(3), 1335-1341.

Johnson, B. N.; Sharma, H.; Mutharasan, R. Torsional and Lateral Resonant Modes of Cantilevers as Biosensors: Alternatives to Bending Modes. Anal. Chem. 2013, 85(3), 1760-1766.

Mutharasan, R. Piezoelectric Excited Millimeter Sized Cantilever Sensors for Measuring Gas Density Changes. Sens. Actuators, B 2013, in press.

Rijal, K.; Mutharasan, R. A method for DNA-based detection of E. coli O157:H7 in proteinous background using piezoelectric-excited cantilever sensors. Analyst 2013, 138 (10), 2943 - 2950

Sharma, H.; Mutharasan, R. Half antibody fragments improve biosensor sensitivity without loss of selectivity. Anal. Chem. 2013, 85(4), 2472–2477.

Sharma, H.; R. Mutharasan. hlyA gene-based sensitive detection of Listeria monocytogenes using a novel cantilever sensor. Anal. Chem. 2013, 85(6), 3222-3228.

Sharma, H.; Mutharasan, R. Rapid and Sensitive Immunodetection of Listeria monocytogenes in Milk using a Novel Piezoelectric Cantilever Sensor. Biosens. Bioelectron. 2013, 45(15), 158–162.

Sharma, H.; Mutharasan, R. Review of Biosensors for Foodborne Pathogens and Toxins. Sens. Actuators, B 2013, 183 (2013), 535–549.

Xu, S.; Mutharasan, R. Mechanical vibration-assisted modulation of E. coli binding to Poly-L-lysine coated biosensor surface. Sens. Actuators, B 2013, 176(1), 1141-1146.

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